List of Known Problems with LockPick

Hey guys,
My wife and I are gearing up for a nationwide road trip in our Prius. It is an 06 w/ Navigation. I am interested in the LockPick 3 (or whatever the most recent version is) for two reasons:
1. Putting in New Addresses to Navigation while in Motion
2. Possibly using the MDF screen for watching movies while we are sleeping in the Prius at various campsites (though a laptop might work fine- but who knows... maybe I will make the stupid decision of watching a movie while in motion).
Anyway, I am seeing that the LockPick causes some various issues. I don't totally understand all of them and more importantly I would like to get a thread going that has a list of all issues that one can expect after the installation of the LockPick.
So could you guys chime in and let me know what issues I can expect if I add the LockPick 3.
thanks
jared