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Influenza 2018-2019 vaccination

Discussion in 'Fred's House of Pancakes' started by tochatihu, Oct 8, 2018.

  1. Rupert B Puppenstein

    Rupert B Puppenstein Active Member

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  2. iplug

    iplug Senior Member

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  3. tochatihu

    tochatihu Senior Member

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  4. tochatihu

    tochatihu Senior Member

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    Measles has a a particularly high infectivity rate. As do polio and whooping cough, but there are other (very sensible) reasons why outbreaks don't pop up every few years for those.

    I was puzzled a bit about high infectivity rate of norovirus. As most know it works 'at the other end'. Most of the answer seems to be the vast number of those viruses launched (sorry it's pretty much true) infectees.

    Ingest tiny (ten? how they assess that?) number of noros, and you join the unfun.. Simply do not know if that # for measles is similarly low.

    ==
    But measles situation seems to be that:

    US vacc rate has steadily averaged >92%

    Localities with (sufficiently) lower vacc rates get outbreaks sporadically. Many other countries in world are standing by with infectees on call. Commercial air travel is on call.

    When outbreaks occur, hundreds get it, get unpleasantly ill, and all or 99.8% or (ideally) all of them survive. This is because US medicine is good at curing them. It costs, from CDC graphics, big money to do so, but there you go.

    ==
    At least those survivors never have to get a measles vaccination! They achieve godlike immunity status. However, sticking them in the first place would have been much cheaper and they'd not have endured this illness. Which is pretty unfun.
     
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  5. tochatihu

    tochatihu Senior Member

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    Oh and there is no norovirus vaccine. Just ask, next time you considering an ocean cruise :eek:
     
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  6. tochatihu

    tochatihu Senior Member

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    One can certainly not assert that no localities with >91% measles vacc rates could host one of these sporadic outbreaks, but as long as that pattern continues to hold, concordance of evidence does what concordance of evidence typically does.
     
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  7. Rupert B Puppenstein

    Rupert B Puppenstein Active Member

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    All of his sources are in the article you refuse to read. Believe what you wish, not all of us are followers and refuse to accept the biased “testing” vaccines go through. I’d suggest getting your MMR every 10 years, because in adults, especially older adults like you, are not protected by the current schedule, assuming your body doesn’t reject immunity. Some of us choose to demand higher standards because we realize that there are many discrepancies in the information the CDC releases. It’s fishy enough that vaccine injury and death reporting is completely voluntary, most doctors are encouraged not to report them, and vaccine manufacturers are protected from lawsuits, but can sue doctors who report injuries or deaths. I believe in some vaccinations, but I’m not naive like you to trust everything the CDC releases about safety, supposed herd immunity, and effectiveness. After all, I was encouraged while pregnant to get the flu and Tdap vaccines. The inserts of those vaccines had category C designations, yet supposedly they wouldn’t harm my unborn child. Not that they had been tested on pregnant women, because it’s unethical, but ethical to give without testing. Another drug I couldn’t take at all during pregnancy was ibuprofen, because it is deemed unsafe during pregnancy, guess what category? That’s right, C. So, you don’t see a discrepancy?

    Keep stirring pots on Prius chat, but I’ve got better things to do than argue with someone who believes in their old age that everything they’ve been told is true, and anyone who questions that is wrong or anti-vax. There is no way we will have an actual outbreak of measles with deaths. It’s impossible, and it’s not because our medicine in the U.S. is so advanced. It’s not. After all, more women die here during pregnancy, childbirth than any other developed country. But, keep believing the U.S. is amazing with healthcare and that’s why people don’t die from the measles. There is a definite difference between male and female viewpoints. Deadly delivery - how childbirth in America is becoming more dangerous | World Economic Forum
     
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  8. iplug

    iplug Senior Member

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    No again, this is old stuff, I have read it all over the years, all debunked in the past; I am quite familiar with your author; you really should read tochatihu's links above.

    Some truth to what you say, some of us are leaders and practice in this field. Do you?

    Thanks for the unsound advice, but I'll keep to sound science for myself and my patients.

    Incorrect again. But then you would know that if you were a physician.

    Again wrong:
    • Pregnancy Category B: Human Papillomavirus, Influenza (Fluarix, FluLaval, Afluria, Flublok, Flucelvax, Fluzone, Fluzone Intradermal, Fluvirin, Fluad, FluMist), Japanese Encephalitis (Ixiaro), Meningococcal (Menveo), Tdap (Boostrix), Meningococcal B.

    Pregnancy and Vaccination | Guidelines and Recommendations by Vaccine | CDC

    How old are you? How old am I? It's great that in your world fabrication counts for reality.

    People can discuss all they want on Priuschat about which vehicles are better, what is a better way for this or that vehicle thing to be done, but no one dies or gets hurt. I've generally kept my professional world at bay here on Priuschat - but there is an ethical obligation here to point out your repeated misinformation. You promote medical illiteracy and that is a danger to the health of others.
     
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  9. Leadfoot J. McCoalroller

    Leadfoot J. McCoalroller Senior Member

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    First year in 6 or 7 that I missed the flu shot. Sure enough, I've spent the last week at home paying for it. Fortunately I didn't have a gig booked this week, and better still I had a previously scheduled doctor appointment on Monday. Another day or two...
     
  10. ETC(SS)

    ETC(SS) The OTHER One Percenter.....

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    I'm really getting lazy about this vaccine thing since retiring from the active reserves in 2012 and one of these days it's REALLY gonna bite me in the backside, particularly since I now kiss just about every small child in my part of the county, every weekday, by proxy thanks to my loving family and church.
    This week they're having a two-for-one special at the daycare center:
    Pink eye (conjunctivitis) and influenza-lite, which I hope is just a garden variety cold.

    I suppose that when I'm getting my tires rotated this Monday at the big box store I'll see if they're still giving them out.
    In my area the flu is just getting into the second act (mid Feb) and even though many sources say that it's 'too late' for the 2018-2019 season, I'm thinking that if they (same big box store) give it, then I'll take it.
    I also need to look into some of the others.....


    I remember in the military they used to sometimes give me a choice about vaccines.....

    ....left arm or right arm? ;)
     
  11. fuzzy1

    fuzzy1 Senior Member

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    Self contradictory? Unless you can guarantee that the right health regimen will eliminate the risk, then it is not 100% preventable.

    And comparing a highly transmissible contagion to a nontransmisslbe mostly lifestyle-induced disease is an absolute farce, for those who have run out of credibility.
     
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  12. iplug

    iplug Senior Member

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    Some of the otherwise healthiest folks I have encountered have spent a lifetime doing farm work. In many ways they shared a large percent of "blue zone" characteristics.

    But for those octogenarians and nonogenarians presenting to the hospital, the afflictions commonly manifesting are significantly associated with cumulative dust/aerosolized soil exposure. Pulmonary diseases, in these otherwise non-smokers, are over-represented compared to their surviving peers.

    Interstitial lung diseases, COPD, and hypersensitivity pneumonitis and much more common and strongly associated with their personal and/or occupational agricultural exposures.

    When such exposures can not be minimized, it would advisable to wear an appropriate respiratory device when exposed to organic and inorganic aerosols, sawing dusts, or other particulates.
     
  13. tochatihu

    tochatihu Senior Member

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    Anyone whose mind is not already made up, or simply seeks additional information on measles, might look at:


    Measles Elimination in the United States | The Journal of Infectious Diseases | Oxford Academic


    It was published in 2004. A long time ago, but not a strong reason to set it aside. Instead, an interested party would browse (readily available) list of 141 articles citing it since. See if any among them provides substantial updates or refutation.

    Because that's what one does, in providing substantial updates or refutation. Cite the prior.

    Dismissing research elusively on basis of its age is not what one does (in science). If it works in informal debate, well, that's another matter.
     
  14. bisco

    bisco cookie crumbler

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    long article in usa today by the head honcho of ny health. makes a good case for vax
     
  15. Rupert B Puppenstein

    Rupert B Puppenstein Active Member

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    52A95652-F78D-4FE5-AEC9-4F65DD2D5694.jpeg ECB271EA-FEAC-447E-A073-07A031246523.jpeg Here are the vaccine inserts from when I was pregnant and asked to get these specific Tdap and Flu shots. Category C.
     
  16. iplug

    iplug Senior Member

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    Some vaccines and formulations categorized C years ago have later been categorized B when pregnancy study data is available or with further studies and formulations.

    But you knew that. You found an old insert of Fluzone which clearly shows above there were no studies done to show harm at that time. But you also know that when the FDA does not know any harm to exist, the default is pregnancy category C until data is available.

    You accused me of being old but you have not kept us current nor told me how old I am and how old you are. Please enlighten us.


    Fluzone is currently listed as pregnancy category B and has been such since at least 2013.

    Pregnancy Category B: A developmental and reproductive toxicity study has been performed in female rabbits at a dose approximately 20 times the human dose (on a mg/kg basis) and has revealed no evidence of impaired female fertility or harm to the fetus due to Fluzone Quadrivalent.

    https://www.fda.gov/downloads/BiologicsBloodVaccines/Vaccines/ApprovedProducts/UCM513242.pdf


    Your insert on INFANRIX also shows above there were no studies done to show harm, so again the default is pregnancy category C until data is available. Yet you know there are studies showing other formulations of Tdap have been studied and are safe:

    BOOSTRIX (Tdap) was approved in the US in 2005.

    Pregnancy Category B : A developmental toxicity study has been performed in female rats at a dose approximately 40 times the human dose (on a mL/kg basis) and revealed no evidence of harm to the fetus due to BOOSTRIX.


    Again here are our choices:
    • Pregnancy Category B: Human Papillomavirus, Influenza (Fluarix, FluLaval, Afluria, Flublok, Flucelvax, Fluzone, Fluzone Intradermal, Fluvirin, Fluad, FluMist), Japanese Encephalitis (Ixiaro), Meningococcal (Menveo), Tdap (Boostrix), Meningococcal B.


    Obstetricians often prescribed what ostensibly are category "C" medications/vaccinations because FDA data doesn't get updated frequently and these physicians stay current with the newest safety studies.
     
    #76 iplug, Feb 15, 2019
    Last edited: Feb 15, 2019
  17. Rupert B Puppenstein

    Rupert B Puppenstein Active Member

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    Those aren’t old inserts. They are from 2016. I got them sent to me from my doctor. Safety data isn’t updated because there are no safety studies done on pregnant women, it’s unethical. The FDA has chosen to change Flu and Pertussis vaccines to Category B recently, without any data proving its safety, just what they believe would be safe. For being a supposed physician, you sure have a lot of time to spend on a forum. So, evidently, you aren’t that dedicated to your patients. With all this time you have, you could research vaccine inserts and how the information in them differs from CDC recommendations. It’s not like vaccine manufacturers can be held liable for injuries, anyway. Have fun!
     
  18. tochatihu

    tochatihu Senior Member

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    "It’s not like vaccine manufacturers can be held liable"

    This is an extremely important point. Hope readers are aware. National Childhood Vaccine Injury Act of 1986 was (at least in part) a response to manufacturers hitting higher barriers in terms of liability insurance. Some were getting out of the business. This was viewed as adverse to the public good. So legislation passed and President Reagan signed

    National Childhood Vaccine Injury Act - Wikipedia

    In 2011 Supreme Court settled Bruesewitz v. Wyeth 6-2 on behalf of Wyeth (the drug company).. This is only test of this law that I know about

    So, the original quote here is narrowly correct. Vaccine manufacturers are operating in a 'protected' environment. As their product is protection, it seems fitting.
     
  19. iplug

    iplug Senior Member

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    Repeating something false does not make it less false.

    No, sorry but you trapped yourself. The inserts you posted above show dates after 2016. An interested reader can see the part that talks about flu season 2018-2019. Why such deception?

    Your trickery involves posting the data for the 372 Fluzone High-Dose for those 65 years of age and older. This is not the regular version of Fluzone given to pregnant patients, although it would very likely be safe to do so, it does not have an FDA indication for that because the regular dose was already studied.

    You intentionally left out the indication section and assumed the non-medical reader who has no special knowledge to know otherwise would not catch that. Shame on you that you would intentionally do such as thing. People's health is at stake here.


    You again intentionally produce falsification.

    Read the above post again; the FDA shows how they came to Pregnancy Category B. You might think yourself clever for trying to confuse the uninformed that human studies are required for safety data, even Category B. They are not, but you know so. You also know that there is copious retrospective data available for all pregnant women who have used Category B therapeutics (and other categories), which are studies themselves.

    Personal insults do not strengthen your argument. You must come up with something factual to defend your very poor position.

    Like most people, physicians have many interests outside of work, including a few minutes to spend on Priuschat on some days. If a few minutes a year on medical topics like this one helps protect the public health from a certain menance of malignant disinformation, it is time well spent. To do otherwise would be medically unethical. Thanks for the extra physician work!
     
    #79 iplug, Feb 15, 2019
    Last edited: Feb 15, 2019
  20. tochatihu

    tochatihu Senior Member

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    Vaccinations for the mind. This metaphor has both unsettling aspects, and prospects for limiting outbreaks of misinformation.

    Perhaps a more benign metaphor would be info available in pill form. One decides which one to ingest.