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SARS-CoV-2 Coronavirus (COVID-19)

Discussion in 'Environmental Discussion' started by tochatihu, Jan 26, 2020.

  1. bisco

    bisco cookie crumbler

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    Good luck Sal
     
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  2. 3PriusMike

    3PriusMike Prius owner since 2000, Tesla M3 2018

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    I guess you did not get the subtle humor...in that a side effect, in an old person, that takes 30 years to show itself is not a big deal

    Mike
     
  3. 3PriusMike

    3PriusMike Prius owner since 2000, Tesla M3 2018

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    I'm guessing here that there is an implicit idea that a virus that was blocked from reproducing in a given host is thus less able to be transmitted to another host because it doesn't exist in a sizable quantity.

    We do know how to prevent virus transmission...it is called a mask or a HEPA filter.

    Mike
     
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  4. bisco

    bisco cookie crumbler

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    sorry, i missed that :oops:
     
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  5. Salamander_King

    Salamander_King Senior Member

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    Aha! Thank you for clarifying this. I guess I am not much behind. In 30 years, I will definitely have other things to worry about if I am still alive then.
     
    #3105 Salamander_King, Dec 4, 2020
    Last edited: Dec 4, 2020
  6. sam spade 2

    sam spade 2 Senior Member

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    Done. The end. Just stop, please.
     
  7. Salamander_King

    Salamander_King Senior Member

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    Gladly!;)
     
  8. bisco

    bisco cookie crumbler

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    no way :cool:
     
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  9. Raytheeagle

    Raytheeagle Senior Member

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    Ignore user:whistle:?

    Keep calm and post on(y).
     
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  10. bisco

    bisco cookie crumbler

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    you can't end an argument if you can't have the last word. especially after telling your opponent to 'just stop'
     
  11. Salamander_King

    Salamander_King Senior Member

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    No argument here. Just a mutual agreement. :whistle:
     
    #3111 Salamander_King, Dec 5, 2020
    Last edited: Dec 5, 2020
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  12. Raytheeagle

    Raytheeagle Senior Member

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    The argument never starts if you never see the post to begin with ;).

    Approaching 3 years on my ignore user list and still seems to be appropriate:).

    Just wish the posts didn't get out of the "c" forums:cool:.

    But I'll control what I can control (y).
     
  13. mjoo

    mjoo Senior Member

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    But if I say it more times than you I must be right.
     
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  14. spiderman

    spiderman wretched

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    Or if you are a super hero and it is the first Saturday of the month, I am right.
     
  15. spiderman

    spiderman wretched

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    Do you even think about what you are writing?
     
  16. Salamander_King

    Salamander_King Senior Member

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    Here is what could be a "silver bullet" for preventing SARS-CoV-2 transmission and break the chain of COVID-19 spread.
    Oral drug blocks SARS-CoV-2 transmission, Georgia State biomedical sciences researchers find | EurekAlert! Science News

    Yeah, the paper is describing the results on the animal model, but if it works in humans, it can really be a breakthrough. The good news is that the drug MK-4482/EIDD-2801 is currently in phase II/III clinical trials already.
    Here is the original reference: https://www.nature.com/articles/s41564-020-00835-2
     
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  17. bisco

    bisco cookie crumbler

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    i sure hope so, this vaccine stuff isn't guaranteed :(
     
  18. Salamander_King

    Salamander_King Senior Member

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    I have not read much about MK-4482/EIDD-2801 (Molnupiravir) development until today. But the drug was originally discovered for its effectiveness in preventing the influenza virus infection. It is a pro-drug consisting of a nucleoside analogue that competes effectively RNA based viral replication. I have to read up on the current clinical trial protocol for this drug, but it seems the drug is administered to patients who tested positive for SARS-CoV-2 infection within 48 hours of PCR confirmation and are hospitalized with a diagnosis of COVID-19. The timing seems to be a bit later than the ideal use of the drug for preventing the initial spreading of the virus. I don't know what pharmacokinetic characteristics this drug has once taken internally. If it's anti-viral effectiveness lasts only a short time, using it prophylactically before the infection may be difficult.
     
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  19. fuzzy1

    fuzzy1 Senior Member

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    Do you read the stuff you refer to?
     
  20. ILuvMyPriusToo

    ILuvMyPriusToo Senior Member

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