Misfire misfire misfire

Hey all….long time listener, first time caller. Got a 2005 with 256k miles on it. We bought it 9 yrs ago and have put about 100k miles on it. The thing has been a tank up until now. Two weeks ago I replaced plugs, coils, injectors and MAF sensor. Drove fine for a week and then got the triangle of death. Problem was an injector was leaking (totally my fault) . Replaced o ring, cleared codes and drove fine until yesterday.

now I’m getting misfires on 2,3&4. It runs, but really rough. I’m just trying to figure out what it could be and I’m running out of ideas. I suppose one of the coils could be bad out of the box but it seems strange to me that it would drive fine. Still get 40+ mpg and then all of a sudden this. Any thoughts, ideas??