Disease Prevention and Health Reseach

Discussion in 'Environmental Discussion' started by tochatihu, Mar 29, 2025.

  1. bisco

    bisco cookie crumbler

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    when do you decide to get a fentanyl vaccine, before deciding to take fentanyl?
     
  2. ChapmanF

    ChapmanF Senior Member

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    If I understand correctly, a lot of people are dying from fentanyl they never decided to take; they decided to take something else, and didn't know their supplier had adulterated it with fentanyl.
     
  3. frodoz737

    frodoz737 Top Wrench

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    A vaccine is a substance that stimulates the body's immune system to protect against...a specific disease. I would suggest vaccine is not the correct word/definition as it applies here.
     
  4. fuzzy1

    fuzzy1 Senior Member

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    On the contrary:

    vaccine noun

    1 ...

    2 : a preparation or immunotherapy that is used to stimulate the body's immune response against noninfectious substances, agents, or diseases [emphasis added]
     
  5. tochatihu

    tochatihu Senior Member

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    The Ars Technica link describes how fentanyl vaccine is prepared and how it elicits antibody responses. I presume that some people read that.
     
  6. Trollbait

    Trollbait It's a D&D thing

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    Will add that the botulism vaccine is against the toxin, not the microbes making it. The vaccine is effective for decades, so botox for wrinkles ain't going to work later in life for those that had the vaccine.
     
  7. bisco

    bisco cookie crumbler

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    i suppose then, if you're going to begin taking illicit drugs, you should get the vaccine first, in case someone decides to slip in some fentanyl
     
  8. frodoz737

    frodoz737 Top Wrench

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    Hey...let's do a nation wide mandatory with Narcan then too. You never when someone might slip us a mickey. :rolleyes:
     
  9. fuzzy1

    fuzzy1 Senior Member

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    There are also unintended exposures to people who don't knowingly take any illicit drugs. These are people who have no built-up resistance, thus most susceptible.
     
  10. bisco

    bisco cookie crumbler

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    when mrs b started on an eczema biologic, they wanted her to get a hep b shot. she refused. i hope we didn't make a mistake.
    what possible non illicit drugs should she avoid?
     
  11. tochatihu

    tochatihu Senior Member

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    New year bring us closer to Grim Reaper’s sickle. Here comparing exit 'strategies'. Not happy thoughts, but quantifying has some merit.

    Main chart is

    causes of death.gif

    From
    https://www.cdc.gov/nchs/nvss/deaths.htm

    Showing COVID decrease from ~104 (2021) to ~45 (2022). Later years can be see at:
    https://gizmodo.com/covid-19-is-still-killing-a-disturbing-number-of-americans-study-finds-2000705483
    https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2843383?guestAccessKey=c26397f8-3193-499d-a048-281b78b4d8b6&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=010526

    Calculating from that, COVID was 30 in 2023 and 30 in 2024. It’s not good news that decrease has stalled.

    Seasonal Influenza is not on NVSS chart. It varies a lot in US year to year:

    https://www.statista.com/statistics/1124915/flu-deaths-number-us/

    Converted to units as above, seasonal Influenza mortality rates ranged from 2 to 16.

    Now you know. As they say.

    ==
    Most of these exit strategies can be partially controlled. Readers might have New Year’s resolutions concerning exercise and healthy eating and drinking.

    COVID and seasonal Influenza offer partial exit-strategy avoidance through vaccinations. Readers might consider these very easy things.
     
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  12. tochatihu

    tochatihu Senior Member

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    Death's sickle or scythe, More study is required but either way it represents harvest. :eek:
     
  13. bisco

    bisco cookie crumbler

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    if you have a population of 100, and 50 die of a certain cause, is the same likelihood that 50 more will die the next year?
    maybe it depends on the cause
     
  14. ChapmanF

    ChapmanF Senior Member

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    Doesn't seem like what I'd normally expect ... unless you also have a high-enough birth/immigration rate to also have a population of 100 next year despite losing 50 this year.
     
  15. bisco

    bisco cookie crumbler

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    yeah, i'm confusing myself.
    when i think of flu, or events like covid, i figure the most vulnerable go first, and the next year there are less vulnerable.
    but i suppose some less vulnerable move into the more vulnerable category every year
     
  16. tochatihu

    tochatihu Senior Member

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  17. tochatihu

    tochatihu Senior Member

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    A bit outside defined scope here but I give myself permission:D

    US currently faces shortage of blood donations:

    Red Cross announces severe emergency blood shortage, calls on Americans to donate - ABC News

    Winter always slows donations, but not medical needs. Yes I'm needling readers.

    --
    US has no strict upper limits on donors' age. Australia is 75 years (soft limit), UK is 72 (soft limit), and China is 55. Age restrictions in other countries are not known to me, but that last one listed has personal impact.
     
  18. ChapmanF

    ChapmanF Senior Member

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    ow
     
  19. tochatihu

    tochatihu Senior Member

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    Decades ago, 18-gauge needles* were finished by mechanical grinding that left burrs. Now I understand they are finished by laser ablation. Whatever accurate details are, such have become much more comfortable in both countries where I have been needled.

    Insertion sting persists because topical disinfectants get dragged 'in'. Could be prevented by a smaller sterile wipe after, at point of attack. I have too little influence on medical procedures to make that change.

    --
    *18-gauge needles are 1.27 mm outside diameter to allow 0.84 mm inside diameter. Red blood cells are 0.007 mm diameter, so these pipes move about 100 RBC across pipe diameter. Smaller needles would have less 'ow', but pressure gradient is low. so donation would take more time. RBCs are also fragile and may fragment on contact with rigid needle wall. Time/ow/fragmentation has been optimized.