Prioritize recommended service

You don't need any of that stuff. You can ask the service adviser where in your owner's manual that shows you need those services. They won't be able to show you, cause they are selling you a bunch of nonsense on a 2021

 

We have never needed anything even remotely similar on the older non-hyrids that we kept more than 200,000 miles either. And they spent most of their lives back when fuel has dirtier and had fewer detergents than now.

 

What’s the miles on it?

FWIW, none of the services you’ve mentioned are in the Toyota USA maintenance schedule. Not to say they’re unnecessary, but some more pressing than others. Going through your list:

1. MAF Cleaner $150

^ I’ve done that once. The sensor looked pristine; I gave it a few shots of CRC brand MAF Sensor Cleaner. It’s literally a 5 minute job; to charge $150 USD for that is larcenous.

2. "Platinum" Fuel System Service $360

^ Not needed

3. Throttle Body Service $146

^ Good to do occasionally, say every 50k miles. Best to remove the throttle body’s hold-down nuts/bolts, lift it off with coolant hoses attached, for better access. Torque value for the nuts/bolts is quite low, 7 lb/ft IIRC<confirmed. quoted price is “ok”.

4. Hybrid Fan Clean/Filter Replacement $366

^ Good to do occasionally, especially if it’s never been done, just to see where it’s at. Doubly so if you regularly transport dogs, for example. It’s about an hours work for an experienced tech, price a bit steep.

I would not bother with an alignment, unless you’re noticing something.

Toyota USA says nothing about brake fluid replacement, but FWIW Toyota Canada recommends tri-yearly or 48k kms, whichever comes first. $150 USD would be a fair price, but those are hard to find these days. There’s a link in my signature on this, to give you some idea of the complexity. (On a phone turn it landscape to see signatures)

 

I've attached a (self-cobbled, not guaranteed) spreadsheet summary of the Toyota USA maintenance schedule for 4th Gen Prius, which is in the Warranty and Maintenance Booklet. If you're missing that it can be downloaded from Tech Info Toyota, under the Manuals tab. You can check the spreadsheet against the official, event-by-event publication.

Something else to consider, that hasn't been mentioned, and is absent from the Toyota USA schedule, is a transaxle fluid replacement. Just my opinion: you can't do a first one too soon, say at 12 months or 10k miles. Then a subsequent change, say at 10 years or 100k miles. Should not cost more than $100~125 through dealership, but...