2010 Prius 2 or 3 or a 2012 C 1 or 2???

"about" the same price....thoughts?
Want to maximize everything...cost/mpg/etc
my commute is 79.8 miles each way...NH to Boston...minor hills... 97% highway (split into about 70% 70mph 30% 60 mph)
the road is asphalt
the wind is generally west-south west
solar glare is minimal
commute is 1:30 p.m. then 2:00 a.m. on way home
on non commute days, mostly city driving with minimal highway, most roads are less than 50 speed limit...

I have to make sure I have all the facts, cause I know how fired up some of you get without all the details...