P2111 after oil leak to 0.25qt left

As you listed, DTC P2111 points to a problem with the throttle control motor or the throttle body. That will probably cost in the high three-digits to repair.

I am wondering what kind of leak would cause 3.5 quarts of oil to disappear over 5 days and 25 miles of driving? How does your friend know that the oil leak only started 5 days ago?

What is being done about that leak, and how much damage was caused to the engine? The potential damage caused by lack of lubrication can result in a much more costly repair (i.e., engine replacement may be required) than the throttle control motor.

 

The low oil "warning" (master warning red triangle light) is not going to happen until the engine oil level has dropped ~2 quarts or more, so the oil leak may have started much more than 5 days ago.

It sounds like the leak has not been repaired yet. My guess is that the car hit substantial road debris which impacted the engine. That may be a fairly costly repair depending upon what engine part was damaged. If your friend is lucky, only the oil pan will need to be replaced or resealed.

Engine coolant flows through the throttle body as a winter de-icing measure. I suppose that when the engine overheated due to lack of lubrication, that might have caused the throttle plate to bind up.

I had previously estimated that the repair price will be in the high three-digits (i.e., $600-$700) if the throttle assembly has to be replaced. This assumes an independent installing a used part.

However, I would caution you that if the independent mechanic has not been trained on Toyota hybrids, it would be better to rely upon Toyota dealer service. For example, will the mechanic know how to invoke inspection mode so that the engine can be made to run continuously for testing purposes.

MSRP on a new throttle body is ~$906 so you can expect that the dealer bill will be around $1,300 or so.

 

I would disconnect 12V battery, clean throttle body, reconnect battery, and drive until code comes back.

 

Sorry, I was answering the question "After the oil pan fixed, what needs to be done to fix the code?"
I would do that first, then see what happens. The disconnecting of the battery should erase the codes.

 

• Set parking brake, gear selector in P, and A/C OFF.
• Turn ignition ON (READY lamp illuminated), then turn ignition OFF.
• Perform the following steps within 60 seconds.
• DO NOT depress the brake pedal. Press and release the Power button twice to enter IG-ON.
• Fully depress and release the accelerator pedal 2x with the gear selector in P position.
• Depress the brake pedal and move the gear selector to N position.
• Fully depress and release the accelerator pedal 2x with the gear selector in N position.
• Depress the brake pedal and move the gear selector back to P position.
• Fully depress and release the accelerator pedal 2x with the gear selector in P position.
• The hybrid system warning on the multi-function display should flash.
• Depress the brake pedal and depress and release the Power button once to turn ignition ON (READY lamp illuminated).
• The IC engine should start and run continuously.

Depending on the year, the MFD will either flash, or in mine (2006) I get the "!Problem!" with the car and it eats up the top of the MFD the whole time (like volume control area).