Wuhan Coronavirus 2019 (COVID-19)

Discussion in 'Environmental Discussion' started by tochatihu, Jan 26, 2020.

  1. bisco

    bisco cookie crumbler

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    WHO is taking considerable flak from some university communicable disease professors for their response to date
     
  2. George W

    George W Active Member

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    CDC: Patient under quarantine at Joint Base San Antonio-Lackland has coronavirus - San Antonio Express-News


    "
    The evacuees at Lackland are not the only people in San Antonio under quarantine.

    Officials noted Sunday that they are also "actively monitoring" Bexar County residents who had returned from China and are being self-quarantined at their homes."

    Not so fun fact. There are now 12 confirmed cases in the United States. One of them here in San Antonio. I'm guessing the other 11 are at other military bases in the Central and West coast of the United States. . Isn't that smart of the World Health Organization?
     
    #222 George W, Feb 13, 2020
    Last edited: Feb 13, 2020
  3. bisco

    bisco cookie crumbler

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    My in laws just came down with the flu. I said, “how do you know?”:whistle:

    And they both had the flu shot
     
    #223 bisco, Feb 13, 2020
    Last edited by a moderator: Feb 14, 2020
  4. George W

    George W Active Member

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    The VA offers the flu shot every year. The year their shot triggered a 2 week respiratory nightmare I stopped getting them. That was about 15 years ago.
     
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  5. tochatihu

    tochatihu Senior Member

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    WHO sitreps here:


    Situation reports


    Newest #24 describes category change. Briefly, confirmed now includes folks with particular features on lung xray and particular travel history. Not only positive DNA tests.

    If readers find another source providing additional detail on this shift, please post.

    I must say that redefinitions do not explain large daily fatality increase.
    ==
    Concerning thread title, adding COVID-19 is perfectly appropriate. We all participate at the pleasure of PriusChat moderators.
     
  6. Prodigyplace

    Prodigyplace Senior Member

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    I reported the other post mentioning it and asked for a change. I guess they are all either asleep or sick. :eek:

    @Tideland Prius are you OK??
     
  7. ILuvMyPriusToo

    ILuvMyPriusToo Active Member

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    Cough, cough, cough
     
  8. ChapmanF

    ChapmanF Senior Member

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    Do I understand correctly that SARS-CoV-2 is the official assigned name for the virus, and that COVID-19 (for coronavirus disease 2019) names the disease in humans caused by that virus?
     
  9. bisco

    bisco cookie crumbler

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    52,000 cases and 1,370 deaths
     
  10. RobH

    RobH Senior Member

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  11. bwilson4web

    bwilson4web i3 and Prime

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    I did not find that section.

    My interests are:
    • latency - time between exposure and initial symptoms
    • clinical assays (I did see use of the SARs to confirm but not rule out COVID-19
    • typical duration of fever, cough, other symptoms
    • when (if) a recovered patient is no longer a source for new cases
    Thanks,
    Bob Wilson
     
  12. iplug

    iplug Senior Member

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    Latest high quality study on this topic:

    Effect of Vitamin C, Hydrocortisone, and Thiamine vs Hydrocortisone Alone on Time Alive and Free of Vasopressor Support Among Patients With Septic ShockThe VITAMINS Randomized Clinical Trial

    The VITAMINS Randomized Clinical Trial

    https://jamanetwork.com/journals/jama/fullarticle/2759414
     
  13. bisco

    bisco cookie crumbler

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    come on, you don't believe in scientific studies, do you? big pharma will never give us the truth
     
  14. George W

    George W Active Member

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    As a younger man I tried a detox that included a superdose of Vitamin C. Made my stomach feel like it was burning.
     
  15. mjoo

    mjoo Senior Member

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    Vitamin C powder and IV get filtered out of your bloodstream in an hour. Liposomal vitamin C achieves high blood concentrations around 8x longer. It's more effective than IV for fighting cancer. Also has very subdued acid taste compared with powder (tastes similar to dilute tomato juice).

    Make it at home: http://www.qualityliposomalc.com

    Pixel XL ?
     
    #235 mjoo, Feb 14, 2020
    Last edited: Feb 14, 2020
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  16. Prodigyplace

    Prodigyplace Senior Member

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  17. bisco

    bisco cookie crumbler

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    There just trying to pump up the stock price
     
  18. tochatihu

    tochatihu Senior Member

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    From WHO sitrep 24

    "Overnight 14,840 cases, including 13,332 clinically diagnosed cases were reported from Hubei. This is the first time China has reported clinically diagnosed cases in addition to laboratory-confirmed cases. For consistency, we report here only the number of laboratory-confirmed cases. WHO has formally requested additional information on the clinically diagnosed cases, in particular when these have occurred in the course of the outbreak and whether suspect cases were reclassified as clinically diagnosed cases."

    I added the emphasis. Other sources defined "clinically diagnosed" as xray plus travel history. Other sources defined "laboratory-confirmed" as presence of genetic sequence(s) peculiar to this virus. I could track down what those were, but I have no doubt in accuracy of either definition.

    Please note that this refers to definitions of these categories. I know of no other site than
    https://ncov.dxy.cn
    that is updating "clinically diagnosed" in China. My concern there is that updates are irregular through time (more than once per day) and I do not have a strict schedule for obtaining numbers on that page.

    Please also note that I have no way to independently verify any numbers in sitreps or ncov. I use them to inform models not all of which I have yet presented here.
     
  19. tochatihu

    tochatihu Senior Member

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  20. tochatihu

    tochatihu Senior Member

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    Vaccine @236. This candidate is a DNA vaccine and I will say some things about that. If there are errors, I or someone else could help with cleanup,

    Corona viruses have RNA. This one was sequenced in early January and made public. It is (nowadays) trivial to made its DNA version. ACGU -> TGCA, with much complexity and detail omitted. Some chunk of that DNA is selected for future use.

    The short unique DNA sequence is not a vaccine. It is first vectored into some friendly bacteria's plasmid with some friendly virus. This is now standard toolbox (believe it or not, and it very much was not when I studied these things in school). That transformed bacteria is the vaccine.

    Vaccine enters Bob Wilson's arm (he said he'd volunteer). Now a benign bacterial infection grows in Petri-Bob. That bacteria has in addition to its normal 'load', an otherwise useless DNA sequence that was added as above.

    Next part is not quite clear to me, but that DNA is transcribed into RNA which to some extent leaks out of bacteria. Various immune cells in Bob (B-cells and T-cells it seems) create antibodies against that RNA sequence.

    Later, if Bob forgets to wear his facemask or wash his hands, maybe this corona virus arrives. Bob's new antibodies against that RNA sequence enter the fight, and super-Bob does not become a statistic.

    ==
    One can appreciate that several steps lie between existence of that altered bacteria, to immunological protection, without unintended side effects. I suppose mice and some other primate will be Petri dishes before any such vaccine has human trials. Company mentioned @236 and several others will carry out those steps (at some expense) before they have a product to sell.

    At least one of the SARS corona virus vaccine candidates worked like that. Completion of their testing was ended when SARS stopped transmitting between humans in the wild.
     
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