SARS-CoV-2 Coronavirus (COVID-19)

There was a recent report on the identification of An 81 nucleotide deletion in SARS-CoV-2 ORF7a identified from sentinel surveillance in Arizona (Jan-Mar 2020).

The theory is that virus is under selective pressure just like any living organism. The mutation that causes the virus to be less lethal to the host would have an advantage over more virulent variants. A weakened virus that causes the less severe disease is able to spread efficiently through populations by people who are infected but stays relatively asymptomatic. This may be what is happening in more recent cases of Covid-19.

 

In the case of viruses, the tried and true treatments for fever and inflammation are going to be true no matter what the disease is.

 

not according to the scientific and medical articles i am reading, but i have no knowledge myself. seems to me they have a lot to learn on this one, and have already learned some things not previously known.

 

I have 2 nieces that are RNs, and one just tested positive for the antibodies, never realizing that she had any bug at all.
She's now working in the COVID ward.

At first I thought that it's not very credible for an RN to have the COVIDS but remain non-symptomatic but My CFO swears that I've had the COVIDS based on a cold that I got just after CHRISTMAS that really walloped me.
I even posted about it.....
Influenza US 2019/2020 and vaccine | Page 4 | PriusChat

So....maybe it's time I got tested.
BUT - how would a 'usta-have-it' fit into the model?
How would this effect morbidity data?

Interesting stuff......

 

1) antibody tests are still iffy

2) research in china is showing some post covid cases lost most antibodies after two weeks

3) lots of people are asymptomatic, haven't read why

 

It seems there will likely be many places in the U.S. where there are large surges of hospitalizations/deaths before winter, but not so likely this will be universal nationwide. Enough, however to show up in nationwide averages with more than a tiny blip.

NYC has cooled off but other less dense places are looking hard to replicate to a significant degree by rolling the dice and upping their game.

 

Yeah, there things, like the blood clots, unique to this virus, but others, like cytokine storms, are complications for many infections. Then anti-virals have different effectiveness on different viruses.

But people sick enough with a respiratory infection to be admitted to a hospital are admitted because of high fever or trouble breathing. Treatments for those symptoms are going to be the same, and doctors aren't going to wait for virus test results to start them for bad cases. treating the symptoms is what we mostly have for viruses to begin with.

Assuming all incoming respiratory cases are COVID isn't going to be a big deal, or cause problems. Considering where testing is at, assuming COVID and testing for the flu might be a better chance of getting a patient the correct treatment.

 

graph at 2207: is that the perfect lag from contact to icu?

 

Considering that we have long known that there is a significant fraction of Covid-19 carriers that remain asymptomatic, I not sure why one would question the credibility of an RN doing the same.

As for your illness in late December, we had something similar in mid December. It walloped the spouse, wasn't as bad for me but still hit in unusual fashion. Lots of other people reported something similar too.

But some retrospective tests of autopsy samples taken back then haven't found Covid-19 earlier than the California death in early February. The Seattle Flu Study has stored samples of live volunteers going back to November, but their move to retrospectively test for Covid-19 was very quickly halted by orders from above, both federal and state, because it wasn't covered by the original consent agreements.

Spouse asked about those December illnesses during a pre-op physical, and was told that a nasty cold variant was running around.

 

Sure was....

I actually looked into the AB test as it is covered by insurance but I'll probably just not worry about it.
It's been > 6 months.
Six of the freeking LONGEST months in recorded human history since the Sitskrieg - or so it seems.

There's lots of questions surrounding the accuracy of these tests and in the end.....I would be left with knowledge that I pretty much already have.

 

Bad hotspot with no peak in sight:

 

Is it in CA? I have a feeling we will see more and more of those resurgent "spikes" despite whatever the 45 claimes. With laxed social distancing and opening of more and more of stores and restaurants, my suspicion is that the second wave is going to be worse than the first one. One opinion I read somewhere stated it is an optimistic view if the US death toll from the COVID-19 to stay under 300K.

Never a big fan of crowded places with too many people. No dining out or bar hopping for a foreseeable future for me.

 

I'll drink to that!

 

Bexar county/ San Antonio, TX. I did my Internal Medicine residency there in the Air Force. Largely suburban city.

There are some hints in the last few days things are starting to heat up with hospitalizations/ICU in the more dense cities of California. But nothing quite like this San Antonio trajectory here (yet).

 

a lot of people still in denial

 

swedens state epidemiologist stands by his decision not to shut down, says that how to handle a virus had been studied for years worldwide, and everyone agreed swedens way was the right way.

'it's almost as if the world has gone mad, and forgotten everything we've learned about viruses' - anders tegnell.
he also claims there's no scientific evidence that masks work...

june 12: swedish home affairs minister mikael damberg says the recent increase in cases is a result of increased testing.

 

national geographic: 'here's how to stop the virus from winning' - nsikan akpan

scientists, docs and data geeks will like this one

 

Here is the link. Here's how to stop the virus from winning
Unfortunately, to read the article you have to give it your e-mail address.

Not a bad perspective article, but it's disappointing to not to find anything close to the answer to the title of the article.

 

it was available on apple news without having to do that.

you didn't buy the harm reduction advice? sounds pretty similar to most of what the experts are saying